London – Melanoma skin cancer cases are rising and are caused by too much exposure to ultraviolet light from the Sun or tanning beds. Getting a tan before going on holiday, has also sparked a fresh warning about the dangers of using a sunbed. Melanoma often starts as a new mole or a change in a mole that people already have. …
Tagrisso with addition of chemotherapy approved in EU
London – AstraZeneca’s Tagrisso (osimertinib) with the addition of pemetrexed and platinum-based chemotherapy has been approved in the European Union (EU) for the 1st-line treatment of adult patients with advanced epidermal growth factor receptor-mutated (EGFRm) non-small cell lung cancer (NSCLC) whose tumours have exon 19 deletions or exon 21 (L858R) mutations. The approval by the European Commission follows the positive opinion of the Committee …
Imfinzi plus chemotherapy doubled overall survival rate
London – Updated exploratory results from the TOPAZ-1 Phase III trial showed AstraZeneca’s Imfinzi (durvalumab) in combination with standard-of-care chemotherapy demonstrated a clinically meaningful long-term overall survival (OS) benefit at three years for patients with advanced biliary tract cancer (BTC). These results from TOPAZ-1, which are the longest survival follow-up ever reported for a global, randomised Phase III trial in this …
Enhertu approved in China
London – AstraZeneca and Daiichi Sankyo’s Enhertu (trastuzumab deruxtecan) has been approved in China as a monotherapy for the treatment of adult patients with unresectable or metastatic HER2-low (IHC 1+ or IHC 2+/ISH-) breast cancer who have received a prior systemic therapy in the metastatic setting or developed disease recurrence during or within six months of completing adjuvant chemotherapy. Enhertu is a …